Theraderm Replacement Guide
Written by Theresa Palella, licensed aesthetician & founder of True Skin Beauty
Updated on May 14, 2026
Theraderm is no longer available, and I know this may come as a surprise. I’ve known the founder, Dr. Beckman, for over 30 years and was trained by him while working with the line, so this change is especially meaningful to me.
The good news—many of my clients have already transitioned to new options and are seeing beautiful results. I’ve personally selected trusted alternatives below that I use and recommend. And if you’d like guidance, I’m always here to help you find what’s best for your skin.
Cleansers & Exfoliation
Theraderm NuPeel Enzyme Peel
Papaya Enzyme Cleanser by Revision Skincare
If you loved your gentle enzyme peel, this is a beautiful alternative—offering the same smoothing and brightening in a daily cleanser.
Exfoliating Cleanser by HydroPeptide
If you're looking for a bit more exfoliation, this cleanser provides a deeper polish while still supporting the skin.
Theraderm Cleansing Face Wash
Gentle Foaming Cleanser by Revision Skincare
A gentle, effective cleanser designed to thoroughly cleanse without stripping the skin. Leaves skin feeling soft, balanced, and comfortable.
Gentle Foaming Cleanser by Epionce
A beautiful calming option that cleanses while helping to keep the skin balanced and comfortable, especially for more sensitive skin.
Theraderm Fruit Acid Exfoliant
Radiance+ Resurfacing Serum by Revision Skincare
A gentle, effective cleanser designed to thoroughly cleanse without stripping the skin. Leaves skin feeling soft, balanced, and comfortable.
Theraderm Brilliance Boost Pads
A.C.E. Treatment Pads by Clinical Skin
A gentle, effective cleanser designed to thoroughly cleanse without stripping the skin. Leaves skin feeling soft, balanced, and comfortable.
AlphaRet Exfoliating Peel Pads by skinbetter science
If you want an upgraded option, these are more advanced pads that combine exfoliation with retinoid technology to visibly improve skin tone, texture, and overall skin quality.
Brightening & Treatment Serums
Theraderm Enlighten Skin Brightener
Clear FX Skin Brightening Cream by Obagi Nu-Derm®
A gentle daily brightening cream designed to help even skin tone and reduce the appearance of discoloration. Very similar in approach to Theraderm's Enlighten Skin Brightener, with a smooth and comfortable finish.
Even Tone Correcting Serum by skinbetter science
If you're willing to upgrade, this is a more advanced brightening serum designed to target uneven tone and discoloration for a clearer, more refined complexion.
Theraderm OPC Reparative Serum
Mystro Active Balance Serum by skinbetter science
The closest feel to Theraderm's OPC Reparative Serum is Mystro—it helps calm, rebalance, and strengthen the skin just like your OPC serum did.
Alto Advanced Defense & Repair Serum by skinbetter science
If you're open to an upgrade, Alto gives you everything your OPC serum did plus stronger protection and brightening.
Retinol & Overnight Treatment
Theraderm Brilliance Night Boost Retinol Repair Crème
Retinol Complete® 0.5 by Revision Skincare
A targeted night treatment designed to smooth, refine, and support skin renewal—helping to improve the look of fine lines and overall skin texture.
AlphaRet Overnight Cream by skinbetter science
If you're willing to upgrade, this is a more advanced option that combines exfoliation with retinoid technology to visibly improve tone, texture, and overall skin quality.
Phyto-Retinol Sleep Serum by True Botanicals
For a more gentle alternative, this is a plant-based option designed to support smoother, more comfortable skin for those who prefer a softer approach.
Eye Treatment
Peptide Repair Eye Creme
D·E·J Eye Cream by Revision Skincare
A comprehensive eye treatment designed to smooth, firm, and support the delicate eye area.
Renewal Eye Cream by Epionce
If your skin leans sensitive, this is a calming, hydrating option to keep the eye area soft and supported.
IntraFuse Treatment Eye Cream by skinbetter science
If you're willing to upgrade, this is a more advanced option designed to target lines and improve the overall look of the eye area.
Lip Care
Theraderm Anti-Aging Lip Complex
Anti-Aging Lip Renewal by Epionce
A smoothing, hydrating lip treatment designed to soften the look of fine lines while keeping lips comfortable and nourished throughout the day.
YouthFull Lip Replenisher® by Revision Skincare
If you're willing to upgrade, this is a more advanced lip treatment designed to hydrate, smooth, and visibly plump while helping to improve the look of fine lines and overall lip definition.
Moisturizers & Barrier Support
Theraderm Peptide Hydrator
Trio Rebalancing Moisture Treatment by skinbetter science
A deeply hydrating moisturizer designed to restore balance and support overall skin health.
D·E·J Face Cream by Revision Skincare
A peptide-rich moisturizer designed to firm, smooth, and support long-term skin structure.
Theraderm Flawless Neck Crème
Nectifirm® Advanced by Revision Skincare
A targeted neck treatment designed to firm, smooth, and improve the look of crepey skin, leaving the neck lifted and refined.
6-Week Perfection Neck Tightening Cream by DefenAge
Upgrade option.
Enriched Facial Moisturizer
DermProtect Barrier Defens by Revision Skincare
A rich, barrier-repair moisturizer designed to deeply hydrate, replenish essential lipids, and leave the skin feeling soft, supported, and comfortable.
Renewal Facial Cream by Epionce
A nourishing cream that helps calm, hydrate, and support the skin barrier while improving overall skin texture.
Gentle Facial Moisturizer
Renewal Lite Facial Lotion by Epionce
A lightweight, calming moisturizer designed to hydrate while supporting the skin barrier, leaving skin soft, balanced, and comfortable.
Hyaluronic Moisture by ISDIN
For normal to dry skin, this is a lightweight cream that delivers lasting hydration while leaving the skin soft, smooth, and comfortable.
Eternox Peptide Crème
D·E·J Face Cream by Revision Skincare
A peptide-rich moisturizer designed to support skin structure, improve firmness, and smooth the appearance of fine lines.
Trio Rebalancing Moisture Treatment by skinbetter science
A hydrating treatment that helps restore balance and improve overall skin quality with a smooth, elegant finish.
Extreme Dry Skin Therapy
Renewal Calming Cream by Epionce
A rich, calming moisturizer designed to deeply hydrate while helping to repair and support the skin barrier. Ideal for dry, sensitive, or compromised skin. While not quite as thick as your previous moisturizer, it provides effective hydration with a more comfortable, elegant finish.
Everything Rescue Balm by True Botanicals
A deeply nourishing balm designed to soothe and protect dry, compromised areas—ideal for sealing in moisture and providing extra comfort where needed. Best used as a targeted treatment rather than an all-over facial moisturizer.
Sun Protection
Theraderm Platinum Protection Facial Sunscreen
Actinica Ultralight Mineral Sunscreen SPF 50+ by ISDIN
A lightweight, ultra-sheer mineral sunscreen that protects while feeling effortless on the skin. Designed for comfortable, everyday wear.
Ageless Ultralight Tinted Mineral Sunscreen SPF 50 by ISDIN
A tinted mineral sunscreen that helps even skin tone while protecting and supporting a more radiant, youthful-looking complexion.
Systems & Kits
Skin Renewal Systems
DefenAge Clinical Power Trio + Kit
A next-generation approach to skincare that builds on the simplicity of a complete routine, designed to help your skin renew itself, not just maintain.
Theraderm Travel Systems
DefenAge Discovery Minis Kit
A next-generation approach to hydration and repair, designed to help your skin renew, not just maintain. This set usually lasts about 5–7 days and is a beautiful way to experience a full routine.
Not Sure What to Choose?
Every skin is different, and the right replacement depends on your goals, sensitivities, and current routine. If you’d like personalized guidance, I offer online skin care consultations where we can walk through your routine together and select the best options for you.
Personalized Skincare, Elevated
For ongoing, personalized support, my Concierge Membership offers a more thoughtful approach to your skin. You’ll receive guidance tailored to your needs, along with priority access to treatments, events, and special offerings throughout the year.